top of page


Prior to Vanderbilt:


16. Dual-Gradient Unified Chromatography: A New Paradigm for Versatility in Simultaneous Multicomponent Analysis. Angew. Chem. Int. Ed. 2022, 61, e202208854.

 Losacco, G.L.; Bennett, R.; Ahmad, I. A. H.; Barrientos, R. C.; DaSilva, J. O.; Dong, Y.; Schuppe, A. W.; Wang, Z.; Aiken, S.; Mangion, I.; Aggarwal, V. K.; Regalado, E. L.

15. Unified Total Synthesis of The Limonoid Alkaloids: Strategies for the Synthesis of Highly Substituted Pyridine Scaffolds. Chem 2022, 8, 2856−2887. (preprint)

Schuppe, A. W.; Liu, Y.; Zhao, Y.; Wang, E.; Lee, J.; Ibarraran, S.; Huang, D.; Loria, J. P.; Newhouse, T. R. 

Full paper TOC.tiff

14. Synthesis of melazolide B, a degraded limonoid and related compounds. Tetrahedron Chem 2022, 100011. (preprint)

Liu, Y.; Schuppe, A. W.; Zhao, Y.; Lee, J.; Newhouse, T. R. 

dearom toc.tiff
OL diene toc.tiff

12. A Dual CuH- and Pd-catalyzed Stereoselective Synthesis of Highly Substituted 1,3-Dienes. Org. Lett. 2021, 23, 8816−8821.

Hou, C.-J.; Schuppe, A. W.; Knippel, J. L.; Ni, A. Z.; Buchwald, S. L.

alkenylation toc .tiff

11. Enantioselective Hydroalkenylation of Olefins with Enol Sulfonates Enabled by Dual Copper Hydride and Palladium Catalysis. J. Am. Chem. Soc. 2021,143, 5330−5335.

Schuppe, A. W.; Knippel, J. L.; Borrajo-Calleja, G. M.; Buchwald, S. L.

carbocation toc.tiff

10. An invocation for computational evaluation of isomerization transforms: cationic skeletal reorganizations as a case study. Nat. Prod. Rep. 2021,38, 510−527.

Schuppe, A. W.; Liu, Y.; Newhouse, T. R.

Pd C-O toc.tiff

9. An Improved Process for the Palladium-Catalyzed C–O Cross-Coupling of Secondary Alcohols. Org. Lett. 2020,14, 5369−5374.

Zhang, H.; Ruiz-Castillo, P.; Schuppe, A. W.; Buchwald, S. L.

HCN toc2.tiff

8. Enantioselective Olefin Hydrocyanation without Cyanide. J. Am. Chem. Soc. 2019,141,18668–18672.

Schuppe, A. W.; Borrajo-Calleja, G. M.; Buchwald, S. L.

granatumine toc.tiff

7. Total Synthesis of (+)-Granatumine A and Related Bislactone Limonoid Alkaloids via a Pyran to Pyridine Interconversion. J. Am. Chem. Soc. 2019, 141, 9191–9196.

Schuppe, A. W.; Zhao, Y.; Liu, Y.; Newhouse, T. R.

Cu ox toc.tiff

6. Copper-Catalyzed Vinylogous Aerobic Oxidation of Unsaturated Compounds with Air. J. Am. Chem. Soc. 2018,140, 5300–5310.

Zhang, H.-J.; Schuppe, A. W.; Pan, S.-T.; Chen, J.-X.; Wang, B.-R.; Newhouse, T. R.; Yin, L.

xpb toc.tiff

5. Total Synthesis of (–)-Xylogranatopyridine B via a Palladium-Catalyzed Oxidative Stannylation of Enones. J. Am. Chem. Soc. 2018,140, 2062–2066.

Schuppe, A. W.; Huang, D.; Chen, Y.; Newhouse, T. R.

gold toc .tiff

4. Scalable synthesis of enaminones utilizing Gold's reagents. Tetrahedron 2017,73, 3643–3651.

Schuppe, A. W.; Cabrera, J. C.; McGeoch, C. L.; Newhouse, T. R.

andirolide toc.tiff

2. Scalable Procedure for the Fragmentation of Hydroperoxides Mediated by Copper and Iron Tetrafluoroborate Salts. Org. Biomol. Chem. 2016,14, 6197–6200.

Huang, D.; Schuppe, A. W.; Liang, M. Z.; Newhouse, T. R.

OBC toc.tiff

1. Computational and Experimental Studies of Phthaloyl Peroxide-Mediated Hydroxylation of Arenes Yield a More Reactive Derivative, 4,5-Dichlorophthaloyl Peroxide. J. Org. Chem. 2015,80, 8084–8095.

Camelio, A. M.; Liang, Y.; Eliasen, A. M.; Johnson, T. C.; Yuan, C.; Schuppe, A. W.; Houk, K. N.; Siegel, D.

oxidation toc.tiff
bottom of page